Sulfamethazine
Lintlha tsa Motheo:
Lebitso la Sehlahisoa: Sulfamethazine
Lebitso le leng: sulfadimethylpyrimidine
Mokhoa oa lik'hemik'hale: C12H14N4O2S
Foromo ea sebopeho:
Boima ba molek'hule: 278.33
Nomoro ea ho kena ea CAS: 57-68-1
Nomoro ea ho kena ea EINECS: 200-346-4
Lintho tsa 'mele le tsa lik'hemik'hale
Boima: 1.392g/cm3
Sebaka se qhibilihang: 197°C
Sebaka se belang: 526.2ºC
Sebaka sa ho benya: 272.1ºC
Ponahalo: phofo e tšoeu ea kristale
Solubility: e batla e sa qhibilihe ka metsing, ha e qhibilihe ka har'a ether, e qhibiliha habonolo ka asiti e hlapollang kapa tharollo ea alkali
Sulfadiazine ke lithibela-mafu tsa sulfanilamide tse nang le mahlaku a tšoanang a antibacterial ho sulfadiazine. E na le liphello tsa antibacterial ho libaktheria tsa enterobacteriaceae tse kang non-zymogenic Staphylococcus aureus, Streptococcus pyogenes, Streptococcus pneumoniae, Escherichia coli, Klebsiella, Salmonella, Shigella, joalo-joalo Neisseria gonorrhoea, Neisseria meningitidis le Haemoenza. Leha ho le joalo, khanyetso ea baktheria ho sehlahisoa e ile ea eketseha, haholo-holo streptococcus, Neisseria le libaktheria tsa Enterobacteriaceae. Li-sulfonamides ke li-bacteriostatic agents tse nang le mefuta e mengata, tse tšoanang ka sebopeho le p-aminobenzoic acid (PABA), e ka khonang ho sebetsa ka tlhōlisano ea dihydrofolate synthetase ka har'a baktheria, kahoo e thibela PABA ho sebelisoa e le lisebelisoa tse tala ho kopanya folate e hlokoang ke baktheria le ho fokotsa palo ea libaktheria. Tetrahydrofolate e sebetsang ka metabolic. Ea ho qetela ke ntho ea bohlokoa bakeng sa motsoako oa purines, thymidine nucleosides le deoxyribonucleic acid (DNA), kahoo e thibela ho hōla le ho ikatisa ha libaktheria.
E sebelisoa haholo bakeng sa mafu a bobebe a bakoang ke libaktheria tse nang le kutloelo-bohloko, joalo ka ts'oaetso e bonolo e tlase ea moroto, acute otitis media le ts'oaetso ea lisele tse bonolo tsa letlalo.
