Methyl 2,2-difluorobenzo[d][1,3]dioxole-5-carboxylate: Thepa le Tshebetso

Methyl 2,2-difluorobenzo[d][1,3]dioxole-5-carboxylateke motsoako oa lik'hemik'hale o nang le foromo ea molek'hule C9H6F2O4 le nomoro ea CAS 773873-95-3. E boetse e tsejoa ka li-synonyms tse 'maloa, tse kang methyl 2,2-difluoro-1,3-benzodioxole-5-carboxylate, 2,2-difluorobenzodioxole-5-carboxylic acid methyl ester, le EOS-61003. Ke ea sehlopha sa metsoako ea heterocyclic e nang le oksijene hetero-athomo feela.

E ithorisa ka bohloeki ba bonyane ba 98%, motsoako ona oa meriana ke tharollo e fapaneng bakeng sa liindasteri tse kang meriana, agrochemicals, le lipatlisiso.Motsoako ona o sebelisoa e le karolo ea bohlokoa ea ho kopanya meriana, pōpo ea lihlahisoa tsa tšireletso ea lijalo, le lipatlisiso tsa saense.

Sehloohong sena, re tla hlalosa thepa e qaqileng ea sehlahisoa le ts'ebetso ea methyl 2,2-difluorobenzo [d] [1,3]dioxole-5-carboxylate, ho latela lintlha tse fumanehang.

Thepa ea 'Mele le ea Lik'hemik'hale

Methyl 2,2-difluorobenzo[d][1,3]dioxole-5-carboxylate ke mokelikeli o mosehla o mosehla o se nang mebala kapa o tiileng, ho latela mocheso le bohloeki. E na le boima ba molek'hule ea 216.14 g/mol le boima ba 1.5±0.1 g/cm3. E na le ntlha e belang ea 227.4±40.0 °C ho 760 mmHg le ntlha ea flash ea 88.9±22.2 °C. E na le khatello e tlase ea mouoane ea 0.1±0.4 mmHg ho 25°C le ho qhibiliha ha metsi ho tlase ho 0.31 g/L ho 25°C. E na le palo ea P ea 3.43, e bontšang hore e qhibiliha haholo ka har'a metsoako ea tlhaho ho feta metsing.

Sebopeho sa methyl 2,2-difluorobenzo[d][1,3]dioxole-5-carboxylate e na le selikalikoe sa benzene se kopantsoeng le reng ea 1,3-dioxole, e nang le liathomo tse peli tsa fluorine le sehlopha sa carboxylate se kopantsoeng le lesale la benzene. . Ho ba teng ha liathomo tsa fluorine ho eketsa botsitso le ts'ebetso ea motsoako, hammoho le lipophilicity le bioavailability. Sehlopha sa carboxylate se ka sebetsa e le sehlopha se tlohang kapa nucleophile ka karabelo e fapaneng. Lesale la 1,3-dioxole le ka sebetsa e le masked glycol kapa dienophile ka liketso tsa cycloaddition.

Tšireletseho le Tšoaro

Methyl 2,2-difluorobenzo[d][1,3]dioxole-5-carboxylate e khetholloa e le ntho e kotsi ho latela Globally Harmonized System of Classification and Labeling of Chemicals (GHS). E na le lipolelo tse latelang tsa kotsi le lipolelo tsa tšireletso:

• H315: E baka ho ruruha ha letlalo

• H319: E baka ho teneha ho hoholo ha mahlo

• H335: E ka baka ho teneha ha phefumoloho

• P261: Qoba ho hema lerole/mosi/gase/moholi/mouoane/hatsa

• P305+P351+P338: HAEBA KA MAHLO: Hlatsoa ka hloko ka metsi ka metsotso e ’maloa. Tlosa lilense tsa ho ikopanya, haeba li le teng ebile ho le bonolo ho li etsa. Tsoela pele ho hlatsoa

• P302+P352: HAEBA U LE LETLALO: Hlatsoa ka sesepa le metsi a mangata.

Mehato ea thuso ea pele bakeng sa methyl 2,2-difluorobenzo [d] [1,3]dioxole-5-carboxylate ke e latelang:

• Ho hema: Ha u hema, isa mokuli moeeng o hloekileng. Haeba ho hema ho le thata, fana ka oksijene. Haeba u sa hema, fana ka phefumoloho ea maiketsetso. Fumana thuso ea bongaka

• Ho ama letlalo: Tlosa liaparo tse silafetseng 'me u hlatsoe letlalo hantle ka sesepa le metsi. Haeba u ikutloa u sa phutholoha, batla thuso ea bongaka

• Ho sheba mahlo: Arola lintši tsa mahlo 'me u hlatsoe ka metsi a phallang kapa saline e tloaelehileng. Batla thuso ea bongaka hang-hang

• Ho noa: Hloekisa, u se ke ua etsa hore motho a hlatse. Batla thuso ea bongaka hang-hang

Mehato ea ts'ireletso ea mollo bakeng sa methyl 2,2-difluorobenzo[d][1,3]dioxole-5-carboxylate ke e latelang:

• Setima-mollo: Tima mollo ka moholi oa metsi, phofo e omeletseng, foam kapa setima-mollo sa carbon dioxide. Qoba ho sebelisa metsi a phallang ka kotloloho ho tima mollo, e leng se ka bakang ho phatloha ha mokelikeli o tukang le ho hasa mollo.

• Likotsi tse khethehileng: Ha ho data e fumanehang

• Mehato ea ho itšireletsa khahlanong le mollo: Basebeletsi ba mollo ba lokela ho apara lisebelisoa tse phefumolohang moeeng, ba apare liaparo tse feletseng tsa mollo le ho loantša moea o fokang. Haeba ho khoneha, tlosa setshelo ho tloha mollong u se ise sebakeng se bulehileng. Lijana tse sebakeng sa mollo li tlameha ho ntšoa hang-hang haeba li fetotsoe kapa li ntša molumo ho tsoa sesebelisoa sa liphallelo. Arola sebaka sa kotsi 'me u thibele basebetsi ba sa amehang ho kena. Kenya le ho hloekisa metsi a mollo ho thibela tšilafalo ea tikoloho

Qetello

Methyl 2,2-difluorobenzo[d] [1,3]dioxole-5-carboxylate ke karolo e bohareng ea motsoako oa meriana, tlhahiso ea lihlahisoa tsa ts'ireletso ea lijalo, le lipatlisiso tsa saense. E na le sebopeho se ikhethileng se nang le liathomo tse peli tsa fluorine le sehlopha sa carboxylate se kopantsoeng le selikalikoe sa benzodioxole, se fanang ka botsitso, reactivity, lipophilicity, le bioavailability ho motsoako. E na le ho qhibiliha ha metsi ho tlase le khatello ea mouoane, le ntlha e belang e itekanetseng le ntlha ea flash. E khetholloa e le ntho e kotsi 'me e hloka ho tšoaroa le ho bolokoa hantle. E na le lits'ebetso tse ka sebelisoang liindastering tse fapaneng, joalo ka tsa meriana, tsa agrochemicals, lipatlisiso le tse ling.

Bakeng sa lintlha tse ling kapa lipotso, ka kopoiteanye le rona:

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