Kenyelletso
Li-nucleosides, li-acid tsa nyutlelie (DNA le Rna), li bapale karolo ea mantlha linthong tsohle tse phelang. Ka ho fetola limolek'hule tsena, bo-rasaense ha ba laole mesebetsi e mengata eo re ka e sebelisang lipatlisisong le tsa bongaka. Sehloohong sena, re tla hlahloba tse ling tsa likopo tsa bohlokoa tsali-nucleosi tse fetotsoeng.
Karolo ea li-nucleo tse fetotsoeng
Modified nucleosides are created by altering the structure of natural nucleosides, such as adenosine, guanosine, cytidine, and uridine. Likhatiso tsena ho ka kenyelletsa liphetoho motheong, tsoekere, kapa ka bobeli ba eona. Sebopeho se fetotsoeng se ka fana ka thepa e ncha ho Nine e fetotsoeng, e e etsa e loketse likopo tse fapaneng.
Likopo tsa Bohlokoa
Ho sibolla lithethefatsi:
Basebeletsi ba Acticelr: Li-Nucleosides tse fetotsoeng li sebelisitsoe ho ntlafatsa lithethefatsi tse fapaneng. Mohlala, li ka re etsetsoa ho itšireletsa ho thibela DNA Syntmeis kapa ho lebisa lisele tse ikhethang tsa mofets'e.
Li-Antiviral Agentude: Nucleoside e fetotsoeng e sebelisoa ho theha litlhare tse thibelang tse thibelang tse ka thibelang ho pheta-phele. Mohlala o tsebahalang ka ho fetisisa ke tšebeliso ea li-nucleode tse fetotsoeng ho Commevid-19 MRNA Counten.
Baemeli ba antibacterial: Li-noneucleseside tse fetotsoeng le tsona li bontšitse ts'episo ho nts'etsopele ea lithibela-mafu.
Boenjiniere ba liphatsa tsa lefutso:
Marena a Irna: Li-NucleO tse fetotsoeng ke likarolo tsa bohlokoa tsa ente ea Irna.
Oligonucleocleotides of Antisense: Limolek'hule tsena tse etselitsoeng ho tlama tatellano ea 'mila, e ka fetoloa ho ntlafatsa tsitsipano le maemo a bona.
Phekolo ea Gener: NUCLEOSITED e fetotsoe ho theha oli e fetotsoeng bakeng sa lits'ebetso tsa Ton Traloret.
Lisebelisoa tsa ho etsa lipatlisiso:
Li-Nucleic Acid: Nucleoside e fetotsoeng e ka kenngoa ka mekhoa e kang fluorescence (tlhapi) le tlhahlobo ea likokoana-hloko.
Baeti: Tsena li angoa ke li-acid tse le 'ngoe tsa nyutlelie e ka fetoloa ho tlama liphofu tse khethehileng, tse kang liprotheine kapa limoleke tse nyane,' me li na le likopo tsa li-spicsostics le bahanyetsi.
Melemo ea Li-NucleO tse fetotsoeng
Ho se tsielehetla e ntlafalitsoeng: Li-NucleO tse fetotsoeng ho ka ntlafatsa botsitso ba atic acic, a li etsa hore li hanyetse haholoanyane ka ho nyenyefatsa ka seritype.
Boholo ba litaba: Liphetoho li ka ntlafatsa tšebelisano-taba ea nyutlei ea Nucleic, e nolofalletsa ho shebiloe ka nepo ea limolek'hule tse tobileng tsa tlhaho.
Ntlafatso ea cellular e ntlafalitse: Li-nucleose tse fetotsoeng li ka etsoa hore li ntlafatsoe sethaleng sa bona sa cellular, ho eketsa katleho ea tsona lits'ebetsong tsa kalafo.
Sephetho
Li-none li fetotse libaka tse feto-fetoheng likarolo tse fapaneng, ho tsoa ho sistimi ea lithethefatsi ho isa boenjiniere ba liphatsa tsa lefutso. Ho feto-fetoha le bokhoni ba bona ho tsamaisa likopo tse khethehileng ho ba etsa lisebelisoa tsa bohlokoa bakeng sa ba bafuputsi le li-clinicas. Ha kutloisiso ea rona ea k'hemik'hale ea nyutleishene e ntse e hola, re ka lebella ho bona lits'ebetso tse ntlafalitsoeng tsa li-nucleode tse fetotsoeng nakong e tlang.
Nako ea poso: Aug-20-2024