C45h56P Bianosine, 5 '-Methyl-1-Methyl- 1-Oxoproite] (1-methyl-

C45h56P Guanosine, 5 '-Methyl-1-Methyl-1-Methyl-1-Methyl-1-methyl-

Tlhahisoleseling ea mantlha:

Romella lengolo-tsoibila ho rona

Lintlha tsa sehlahisoa

Li-tag tsa lihlahisoa

Lintlha tsa ntho

Nomoro ea ho re ngolisa

150780-67-9

H303

Thepa ea bohlokoa ea 'mele	Boleng	Boemo
Boima ba Molecular	869.94	-
pka (e boletsoeng esale pele)	9.16 ± 0.20	Boholo ba tempele ea acidic: 25 ° C

Mabitso a mang le khethollo

N # cccop (OC1C (OC (N2c = NC = NC3 (= CC4) C1 = C6) c

Isomerica e bososela

C (OC [OC @@ H] 1 [C @@ H] (OP (C (C.) C = C4) (C5 = CC = C (OC) C = C5) C6 = CC = C6 = C6

Inchi

Inchi = 1S / C45h5677o9p / C1-28 (2) 41 (44) 43-39) 38 (59-62 (59-62 (59-62 (59-62 (59-62 (59-62 (59-62 (59-62 (59-62 (59-62 (59-62 (59-62 (59-62 (59-62 (59-62 (59-62 (59-62 (59-62 (59-62 (59-62 (59-62 (59-62 (59-62 (59-62 (59-62 (59-62 (59-62 (59-62 (59-62 (59-62 (59-62 (59-62 (59-62 (59-62 (59-62 (59-62 (59-62 (59-62 (59-62 (59-62 (59-62 (59-62 (59-62

46) 52 (29 (3) 4) 30 (5) 6) 26-5) -3,36,38-39 49,53h, 13,25-26H2,25-261

Senotlolo sa Inchi

Irrdhrzuoznwdj-mlldkzsosa-n

1 Lebitso le leng bakeng sa ntho ena

Guanosine, 5 '-O- [Bis (4-Meydoxl) PhenylMEthyl] -2 '-O-Mothyl-N- (2-methyl-1-Oxopropyl) -, 3 '- Cyanooethyl bis

Tekanyetso ea pono ea liteko

Spectra e fumanehang
13 c nmr
Hetero nmr

Lipapatso tse boletsoeng esale pele

Thepa e fumanehang
Sa tlhaho
Lik'hemik'hale
LIPINSSKI
Sebopeho se amanang le

Sa tlhaho

Thepa	Boleng	Boemo	Mohloli
Linkho tsa BioCentration	183	ph 1; TEMP: 25 ° C	(1) ACD
Linkho tsa BioCentration	3890	ph 2; TEMP: 25 ° C	(1) ACD
Linkho tsa BioCentration	35500	ph 3; TEMP: 25 ° C	(1) ACD
Linkho tsa BioCentration	1.08 x 105	PH 4; TEMP: 25 ° C	(1) ACD
Linkho tsa BioCentration	1.36 x 105	ph 5; TEMP: 25 ° C	(1) ACD
Linkho tsa BioCentration	1.39 x 105	PH 6; TEMP: 25 ° C	(1) ACD
Linkho tsa BioCentration	1.38 x 105	PH 7; TEMP: 25 ° C	(1) ACD
Linkho tsa BioCentration	1.24 x 105	PH 8; TEMP: 25 ° C	(1) ACD
Linkho tsa BioCentration	63600	ph 9; TEMP: 25 ° C	(1) ACD
Linkho tsa BioCentration	11900	ph 10; TEMP: 25 ° C	(1) ACD

Lik'hemik'hale

Thepa	Boleng	Boemo	Mohloli
Koc	220	ph 1; TEMP: 25 ° C	(1) ACD
Koc	4680	ph 2; TEMP: 25 ° C	(1) ACD
Koc	42600	ph 3; TEMP: 25 ° C	(1) ACD
Koc	1.30 x 105	PH 4; TEMP: 25 ° C	(1) ACD
Koc	1.63 x 105	ph 5; TEMP: 25 ° C	(1) ACD
Koc	1.67 x 105	PH 6; TEMP: 25 ° C	(1) ACD
Koc	1.65 x 105	PH 7; TEMP: 25 ° C	(1) ACD
Koc	1.49 x 105	PH 8; TEMP: 25 ° C	(1) ACD

Thepa	Boleng	Boemo	Mohloli
Koc	76400	ph 9; TEMP: 25 ° C	(1) ACD
Koc	14200	ph 10; TEMP: 25 ° C	(1) ACD
logd	4.9	ph 1; TEMP: 25 ° C	(1) ACD
logd	5.52	ph 2; TEMP: 25 ° C	(1) ACD
logd	6.48	ph 3; TEMP: 25 ° C	(1) ACD
logd	6.96	PH 4; TEMP: 25 ° C	(1) ACD
logd	7.06	ph 5; TEMP: 25 ° C	(1) ACD
logd	7.07	PH 6; TEMP: 25 ° C	(1) ACD
logd	7.07	PH 7; TEMP: 25 ° C	(1) ACD
logd	7.02	PH 8; TEMP: 25 ° C	(1) ACD
logd	6.73	ph 9; TEMP: 25 ° C	(1) ACD
logd	6.00	ph 10; TEMP: 25 ° C	(1) ACD
Logp	7.072 ± 0.721	TEMP: 25 ° C	(1) ACD
Mass Interrincic solubility	1.2 x 10-4 g / l	TEMP: 25 ° C	(1) ACD
Mass Slisedity	0.096 g / l	ph 1; TEMP: 25 ° C	(1) ACD
Mass Slisedity	4.3 x 10-3 g / l	ph 2; TEMP: 25 ° C	(1) ACD
Mass Slisedity	4.8 x 10-4 g / l	ph 3; TEMP: 25 ° C	(1) ACD
Mass Slisedity	1.6 x 10-4 g / l	PH 4; TEMP: 25 ° C	(1) ACD
Mass Slisedity	1.2 x 10-4 g / l	ph 5; TEMP: 25 ° C	(1) ACD
Mass Slisedity	1.2 x 10-4 g / l	PH 6; TEMP: 25 ° C	(1) ACD
Mass Slisedity	1.2 x 10-4 g / l	PH 7; TEMP: 25 ° C	(1) ACD
Mass Slisedity	1.4 x 10-4 g / l	PH 8; TEMP: 25 ° C	(1) ACD
Mass Slisedity	2.7 x 10-4 g / l	ph 9; TEMP: 25 ° C	(1) ACD
Mass Slisedity	1.4 x 10-3 g / l	ph 10; TEMP: 25 ° C	(1) ACD
Mass Slisedity	1.2 x 10-4 g / l	Ph ea metsi e sa sebetsoeng 7.00; TEMP: 25 ° C	(1) ACD
Molala oa Molala oa Molala	1.4 x 10-7 Mol / L	TEMP: 25 ° C	(1) ACD
Molala ea lla	1.1 x 10-4 mol / L	ph 1; TEMP: 25 ° C	(1) ACD
Molala ea lla	5.0 x 10-6 mol / L	ph 2; TEMP: 25 ° C	(1) ACD
Molala ea lla	5.5 x 10-7 Mol / L	ph 3; TEMP: 25 ° C	(1) ACD
Molala ea lla	1.8 x 10-7 Mol / L	PH 4; TEMP: 25 ° C	(1) ACD
Molala ea lla	1.4 x 10-7 Mol / L	ph 5; TEMP: 25 ° C	(1) ACD
Molala ea lla	1.4 x 10-7 Mol / L	PH 6; TEMP: 25 ° C	(1) ACD

Thepa	Boleng	Boemo	Mohloli
Molala ea lla	1.4 x 10-7 Mol / L	PH 7; TEMP: 25 ° C	(1) ACD
Molala ea lla	1.6 x 10-7 Mol / L	PH 8; TEMP: 25 ° C	(1) ACD
Molala ea lla	3.1 x 10-7 Mol / L	ph 9; TEMP: 25 ° C	(1) ACD
Molala ea lla	1.6 x 10-6 mol / L	ph 10; TEMP: 25 ° C	(1) ACD
Molala ea lla	1.4 x 10-7 Mol / L	Ph ea metsi e sa sebetsoeng 7.00; TEMP: 25 ° C	(1) ACD
Boima ba Molecular	869.94
pka	9.16 ± 0.20	Boholo ba tempele ea acidic: 25 ° C	(1) ACD
pka	3.45 ± 0.70	Boholo ba mosebetsi oa mantlha: 25 ° C	(1) ACD

LIPINSSKI

Thepa	Boleng	Boemo	Mohloli
Li-litlama tse potolohileng ka bolokolohi	19		(1) ACD
H	16		(1) ACD
H donors	2		(1) ACD
H donor / Canot	18		(1) ACD
Logp	7.072 ± 0.721	TEMP: 25 ° C	(1) ACD
Boima ba Molecular	869.94