7-Amino-3-cephem-4-carboxylic acid
Lintlha tsa Motheo:
Lebitso la Senyesemane:
7-ANCA;7-AMOCA;(6R,7R)-7-AMino-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicAcid;7-NACA;7- NACA,7-ANCA;7-ANCAChemicalbook bohloeki;CeftizoximeBohloeki9;CeftizoximeBohloeki16;Ceftizoximeintermediate(7-anca);7-amino-3-cephem-4-carboxylicacid
Nomoro ea CAS: 36923-17-8
Foromo ea molek'hule: C7H8N2O3S
Boima ba molek'hule: 200.21
Nomoro ea EINECS: 609-312-7
Foromo ea sebopeho:
Likarolo tse amanang: Li-intermediate tsa Organic; Li-intermediates tsa meriana; Lisebelisoa tse tala tsa meriana.
Sebaka se qhibilihang: 215-218°C
Sebaka se belang: 536.9±50.0 °C(Ho Boletsoe esale pele)
Boima: 1.69± 0.1g /cm3(E boletsoeng esale pele)
Lenane la refractive: 1.735 (khakanyo)
Sebaka sa ho benya: 278.508°C
Solubility: E qhibiliha ka har'a motsoako oa asiti ea metsi (e nyenyane, e futhumetseng), DMSO (e nyenyane). Thepa: phofo e tšoeu kapa e tšoeu ea kristale.
Khatello ea mouoane: 0mmHg ho 25°C
| tlhaloso | unit | maemo |
| Ponahalo | Phofo e tšoeu kapa e tšoeu ea kristale | |
| Litaba tsa mantlha | % | ≥98.5% |
| Mongobo | % | ≤1 |
| Mono hybrid | % | ≤0.5 |
| Bohlasoa bo felletseng | % | ≤1 |
Cephalosporin, e sebelisoang e le setsi sa mahareng sa cefbutan le cefazoxime.
Concentrated sulfuric acid (104.3mL, 1.92mol) e kentsoe ka libotlolong tse tharo, ebe isophthalic acid (40g, 0.24mol) ea eketsoa, ea hlohlelletsoa le ho futhumatsoa ho 60 ℃, e tšoaretsoeng 0.5h, le 60% nitric acid (37.8g, 0.36) mol) e ile ea eketsoa ho laola tekanyo ea ho potlakisa marotholi. E kenye ka mor'a lihora tse 2. Kamora ho ekelletsa, karabelo ea ho boloka mocheso ho 60 ℃ bakeng sa lihora tse 2. Pholisa ho fihlela ka tlase ho 50 ° C, ebe u eketsa 100mL ea metsi. Thepa e ne e pholile ka mocheso oa kamore, e tšeloa ka har'a filthara, e pompetsoe ho tlosa acid e litšila, kaka ea filthara e ne e hlatsuoa ka metsi, e tšolotsoe ho tsosolosa, 'me sehlahisoa se tšoeu e ne e le ligrama tse 34,6, chai e ne e le 68,4%.
20Kg kapa 25Kg/ bakete, bakete ea khateboto, e nang le lesela le lesoeu le mokotla o motšo oa polyethylene. 2 ℃-8 ℃ sebaka se omeletseng, se phodileng, hole le polokelo e bobebe, se sebetsa lilemo tse 2.
