![118 Re36H44N2O8Si Uridine, 5′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′-O-[(1,1- dimethylethyl)dimethylsilyl]- (9CI, ACI)](http://cdn.globalso.com/nvchem/style/global/img/demo/page_banner.jpg)
![118 Re36H44N2O8Si Uridine, 5′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′-O-[(1,1- dimethylethyl)dimethylsilyl]- (9CI, ACI) Setšoantšo se Featured](https://cdn.globalso.com/nvchem/118-Re36H44N2O8Si-Uridine.jpg)
118 Re36H44N2O8Si Uridine, 5′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′-O-[(1,1- dimethylethyl)dimethylsilyl]- (9CI, ACI)
| Lintho Tsa Bohlokoa Tsa 'Mele | Boleng | Boemo |
| Boima ba Molek'hule | 660.83 | - |
| Boima (bo boletsoeng esale pele) | 1.24±0.1 g/cm3 | Mocheso: 20 °C; Tobetsa: 760 Torr |
| pKa (E boletsoeng esale pele) | 9.39±0.10 | Mocheso o nang le Asiti ka ho Fetisisa: 25 °C |
Canonical SMILES O=C1C=CN(C(=O)N1)C2OC(COC(C=3C=CC=CC3)(C4=CC=C(OC)C=C4)C5=CC=C(OC)C=C5)C(O)C2O[Si](C)(C)C(C)(C)C
Isomeric SOSOA
C(OC[C@H]1O[C@H]([C@H](O[Si](C(C)(C)C)(C)C)[C@@H]1O)N2C(=O)NC(=O)C=C2)(C3=CC=C(OC)C=C3)(C4=CC=C(OC)C5=CC=C4)
InChi
InChI=1S/C36H44N2O8Si/c1-35(2,3)47(6,7)46-32-31(40)29(45-33(32) )38-22-21-30(39)37-34(38)41)23-44-36(24-11-9-8-10-12-24,25-13- 17-27(42-4)18-14-25)26-15-19-28(43-5)20-16-26/h8-22,29,31-33,40H,23H2,1-7H3,(H,37,39,41)/t29-1-26/s1
Senotlolo sa InChi
KVHQIELPHWJPSY-WXQJYUTRSA-N
2 Mabitso a Mang a Ntho ena
5′-O-[Bis(4-methoxyphenyl)phenylmethyl]-2′-O-[(1,1-dimethylethyl)dimethylsilyl]uridine (ACI); 2′-O-tert-Butyldimethylsilyl-5′-O-(4,4′- dimethoxytrityl)uridine
Spectra e fumaneha
1H NMR
13C NMR
Hetero NMR
Mmisa
| Thepa e teng |
| Likokoana-hloko |
| Lik'hemik'hale |
| Botenya |
| Lipinski |
| Sebopeho se Amanang |
Likokoana-hloko
| Thepa | Boleng | Boemo | Mohloli |
| Bioconcentration Factor | 2.21 x 105 | pH 1; Mocheso: 25 °C | (1) ACD |
| Bioconcentration Factor | 2.21 x 105 | pH 2; Mocheso: 25 °C | (1) ACD |
| Bioconcentration Factor | 2.21 x 105 | pH 3; Mocheso: 25 °C | (1) ACD |
| Bioconcentration Factor | 2.21 x 105 | pH 4; Mocheso: 25 °C | (1) ACD |
| Bioconcentration Factor | 2.21 x 105 | pH 5; Mocheso: 25 °C | (1) ACD |
| Bioconcentration Factor | 2.21 x 105 | pH 6; Mocheso: 25 °C | (1) ACD |
| Bioconcentration Factor | 2.20 x 105 | pH 7; Mocheso: 25 °C | (1) ACD |
| Bioconcentration Factor | 2.12 x 105 | pH 8; Mocheso: 25 °C | (1) ACD |
| Bioconcentration Factor | 1.54 x 105 | pH 9; Mocheso: 25 °C | (1) ACD |
| Bioconcentration Factor | 42500 | pH 10; Mocheso: 25 °C | (1) ACD |
(1) E baloang ho sebelisoa Advanced Chemistry Development (ACD/Labs) Software V11.02 (© 1994-2023 ACD/Labs)
Lik'hemik'hale
| Thepa | Boleng | Boemo | Mohloli |
| Koc | 2.33 x 105 | pH 1; Mocheso: 25 °C | (1) ACD |
| Koc | 2.33 x 105 | pH 2; Mocheso: 25 °C | (1) ACD |
| Koc | 2.33 x 105 | pH 3; Mocheso: 25 °C | (1) ACD |
| Koc | 2.33 x 105 | pH 4; Mocheso: 25 °C | (1) ACD |
| Koc | 2.33 x 105 | pH 5; Mocheso: 25 °C | (1) ACD |
| Koc | 2.33 x 105 | pH 6; Mocheso: 25 °C | (1) ACD |
| Thepa | Boleng | Boemo | Mohloli |
| Koc | 2.32 x 105 | pH 7; Mocheso: 25 °C | (1) ACD |
| Koc | 2.23 x 105 | pH 8; Mocheso: 25 °C | (1) ACD |
| Koc | 1.62 x 105 | pH 9; Mocheso: 25 °C | (1) ACD |
| Koc | 44800 | pH 10; Mocheso: 25 °C | (1) ACD |
| logD | 7.33 | pH 1; Mocheso: 25 °C | (1) ACD |
| logD | 7.33 | pH 2; Mocheso: 25 °C | (1) ACD |
| logD | 7.33 | pH 3; Mocheso: 25 °C | (1) ACD |
| logD | 7.33 | pH 4; Mocheso: 25 °C | (1) ACD |
| logD | 7.33 | pH 5; Mocheso: 25 °C | (1) ACD |
| logD | 7.33 | pH 6; Mocheso: 25 °C | (1) ACD |
| logD | 7.33 | pH 7; Mocheso: 25 °C | (1) ACD |
| logD | 7.32 | pH 8; Mocheso: 25 °C | (1) ACD |
| logD | 7.18 | pH 9; Mocheso: 25 °C | (1) ACD |
| logD | 6.62 | pH 10; Mocheso: 25 °C | (1) ACD |
| logP | 7.334±0.643 | Mocheso: 25 °C | (1) ACD |
| Mass Intrinsic Sollubility | 3.5 x 10-5 g/L | Mocheso: 25 °C | (1) ACD |
| Ho qhibiliha ka bongata | 3.5 x 10-5 g/L | pH 1; Mocheso: 25 °C | (1) ACD |
| Ho qhibiliha ka bongata | 3.5 x 10-5 g/L | pH 2; Mocheso: 25 °C | (1) ACD |
| Ho qhibiliha ka bongata | 3.5 x 10-5 g/L | pH 3; Mocheso: 25 °C | (1) ACD |
| Ho qhibiliha ka bongata | 3.5 x 10-5 g/L | pH 4; Mocheso: 25 °C | (1) ACD |
| Ho qhibiliha ka bongata | 3.5 x 10-5 g/L | pH 5; Mocheso: 25 °C | (1) ACD |
| Ho qhibiliha ka bongata | 3.5 x 10-5 g/L | pH 6; Mocheso: 25 °C | (1) ACD |
| Ho qhibiliha ka bongata | 3.5 x 10-5 g/L | pH 7; Mocheso: 25 °C | (1) ACD |
| Ho qhibiliha ka bongata | 3.6 x 10-5 g/L | pH 8; Mocheso: 25 °C | (1) ACD |
| Ho qhibiliha ka bongata | 5.0 x 10-5 g/L | pH 9; Mocheso: 25 °C | (1) ACD |
| Ho qhibiliha ka bongata | 1.9 x 10-4 g/L | pH 10; Mocheso: 25 °C | (1) ACD |
| Ho qhibiliha ka bongata | 3.5 x 10-5 g/L | Metsi a sa tsitsang pH 7.00; Mocheso: 25 °C | (1) ACD |
| Molar Intrinsic Solubility | 5.3 x 10-8 mol/L | Mocheso: 25 °C | (1) ACD |
| Molar Solubility | 5.3 x 10-8 mol/L | pH 1; Mocheso: 25 °C | (1) ACD |
| Molar Solubility | 5.3 x 10-8 mol/L | pH 2; Mocheso: 25 °C | (1) ACD |
| Molar Solubility | 5.3 x 10-8 mol/L | pH 3; Mocheso: 25 °C | (1) ACD |
| Molar Solubility | 5.3 x 10-8 mol/L | pH 4; Mocheso: 25 °C | (1) ACD |
| Thepa | Boleng | Boemo | Mohloli |
| Molar Solubility | 5.3 x 10-8 mol/L | pH 5; Mocheso: 25 °C | (1) ACD |
| Molar Solubility | 5.3 x 10-8 mol/L | pH 6; Mocheso: 25 °C | (1) ACD |
| Molar Solubility | 5.3 x 10-8 mol/L | pH 7; Mocheso: 25 °C | (1) ACD |
| Molar Solubility | 5.5 x 10-8 mol/L | pH 8; Mocheso: 25 °C | (1) ACD |
| Molar Solubility | 7.6 x 10-8 mol/L | pH 9; Mocheso: 25 °C | (1) ACD |
| Molar Solubility | 2.8 x 10-7 mol/L | pH 10; Mocheso: 25 °C | (1) ACD |
| Molar Solubility | 5.3 x 10-8 mol/L | Metsi a sa tsitsang pH 7.00; Mocheso: 25 °C | (1) ACD |
| Boima ba Molek'hule | 660.83 | ||
| pKa | 9.39±0.10 | Mocheso o nang le Asiti ka ho Fetisisa: 25 °C | (1) ACD |
(1) E baloang ho sebelisoa Advanced Chemistry Development (ACD/Labs) Software V11.02 (© 1994-2023 ACD/Labs)
Botenya
| Thepa | Boleng | Boemo | Mohloli |
| Botenya | 1.24±0.1 g/cm3 | Mocheso: 20 °C; Tobetsa: 760 Torr | (1) ACD |
| Molumo oa Molar | 528.8±5.0 cm3/mol | Mocheso: 20 °C; Tobetsa: 760 Torr | (1) ACD |
(1) E baloang ho sebelisoa Advanced Chemistry Development (ACD/Labs) Software V11.02 (© 1994-2023 ACD/Labs)
Lipinski
| Thepa | Boleng | Boemo | Mohloli |
| Li-Bonds tse ka fetolehang ka bolokolohi | 13 | (1) ACD | |
| H Ba amohelang | 10 | (1) ACD | |
| H Bafani | 2 | (1) ACD | |
| H Kakaretso ea Mofani/Moamoheli | 12 | (1) ACD | |
| logP | 7.334±0.643 | Mocheso: 25 °C | (1) ACD |
| Boima ba Molek'hule | 660.83 |
(1) E baloang ho sebelisoa Advanced Chemistry Development (ACD/Labs) Software V11.02 (© 1994-2023 ACD/Labs)
Sebopeho se Amanang
| Thepa | Boleng | Boemo | Mohloli |
| Sebaka sa Polar Surface | 116 A2 | (1) ACD | |
(1) E baloang ho sebelisoa Advanced Chemistry Development (ACD/Labs) Software V11.02 (© 1994-2023 ACD/Labs)
Spectra e fumaneha
1H NMR
13C NMR
![C30H28N2O7 6H-Furo[2′,3′:4,5]oxazolo[3,2-a]pyrimidin-6-one, 2-[[bis(4-methoxy phenyl)phenylmethoxy]methyl]-2,3,3a,9a-tetrahydro-3-hydroxy-, (3a-CIR) (2R) ACIR,9a](https://cdn.globalso.com/nvchem/C30H28N2O7-6H-Furo-300x300.jpg)
![C50H60N5O10P Cytidine, N-benzoyl-5′ -O- [bis(4-methoxyphenyl)phenylmethyl]-2′ -O- (2-methoxyethyl)- 5-methyl-, 3′ – [2-cyanoethyl N,N-bis(1-methylethyl) phosphoramidite]](https://cdn.globalso.com/nvchem/C50H60N5O10P-Cytidine-300x300.png)
![C41H49FN5O8P Cytidine, N-acetyl-5′ -O- [bis(4-methoxyphenyl)phenylmethyl]-2′ – deoxy-2′ -fluoro-, 3′ – [2-cyanoethyl N,N-bis(1-methylethyl)phosphor amidite] (ACI)](https://cdn.globalso.com/nvchem/C41H49FN5O8P-Cytidine-300x300.png)
![C44H53FN7O8 Guanosine, 5′ -O- [bis(4-methoxyphenyl)phenylmethyl]-2′ -deoxy-2′ – fluoro-N-(2-methyl-1-oxopropyl)-, 3′ – [2-cyanoethyl N,N-bis(1-methylpho ethyl)](https://cdn.globalso.com/nvchem/C44H53FN7O8-300x300.png)